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Immunofluorescence method of determining HBc-antibodies in the blood sera of serum hepatitis type B patients

Zhilina, N.N.; Ketiladze, E.S.

Voprosy Virusologii 25(4): 414-417

1979

ISSN/ISBN: 0507-4088
PMID: 384680
Document Number: 146866
The indirect immunofluorescent procedure was used to examine blood sera from 68 patients with serum hepatitis having HBsAg. HBcAb were found in 85% of the specimens. Formalin-fixed paraffin sections of autopsy livers pretreated with enzyme and containing HBcAg in hepatocyte nuclei were shown to be a useful tissue substrate. HBcAb were found in patients in a wave-like manner. The presence of HBcAb was found to be connected with the active phase of serum hepatitis.

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