Cadaveric graft survival, clinical course, blood transfusion, HLA (A and B) match, and DR match in adult patients transplanted in one centre
Van Hooff, J.P.; van Es, A.; Persijn, G.G.; van Hooff-Eykenboom, I.J.; Kalff, M.W.; van Rood, J.J.; de Graeff, J.
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association 16: 359-365
1979
ISSN/ISBN: 0071-2736 PMID: 398507 Document Number: 146202
The influence of blood transfusions, HLA, A and B, DR matching was studied in adult patients transplanted in one centre. The conclusions were: 1. Pre-transplant blood transfusion(s) are a prerequisite for graft acceptance. 2. In transfused patients with no HLA A and B mismatch, there is only 8% graft loss due to irreversible rejection. 3. In transfused patients with a functioning graft after six months, a decrease in the number of reversible rejection crises is observed in patients with no HLA A and B mismatch or with identity for HLA B7 or HLA B8. 4. Identity for HLA B7 or B8 also gives a higher chance of a late onset of the first rejection crisis.