A double-blind trial of zinc supplementation in pregnancy
Simmer, K.; Lort-Phillips, L.; James, C.; Thompson, R.P.
European Journal of Clinical Nutrition 45(3): 139-144
1991
ISSN/ISBN: 0954-3007 PMID: 2065637 Document Number: 146
A double-blind randomised trial of oral zinc supplementation was carried out during the last two trimesters of pregnancy. Fifty-six women at risk of delivering a small-for-gestational-age baby received either zinc supplement (22.5 mg daily) or placebo. Twenty-nine of the women were compliant. Zinc significantly reduced the incidence of intrauterine growth retardation, and most measured indices of labour and fetal health were better in the supplemented group. Larger studies are now needed to confirm a role for selective zinc supplementation in at-risk pregnancies.
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