Effect of cesium ions on the electrotropic actions of acetylcholine in the rabbit atrium
Nilius, B.; Boldt, W.
Acta Biologica et Medica Germanica 38(8): 1175-1182
1979
ISSN/ISBN: 0001-5318 PMID: 532495 Document Number: 145875
Cs+ (15-20 mM) decreases the electrotropic vagal effects on an isolated vagal innervated rabbit atrium. By means of investigating the action potentials and the phase plane trajectories of trabeculae from the rabbit atrium using a modified single sucrose gap technique the anomalous rectification disappears and also the effect of acetylcholine (ACh) on action potential duration. We presume that the anomalous rectification should be a necessary condition of electrotropic vagal (ACh) action on the rabbit atrium.