Ox kidney uricase: a new method of purification

Farina, B.; Faraone Mennella, M.R.

Italian Journal of Biochemistry 28(4): 261-269

1979


ISSN/ISBN: 0021-2938
PMID: 521256
Document Number: 144519
A purification procedure of uricase from ox kidneys has been worked out starting from a n-butanol extract. Gel filtration and ion-exchange chromatography give a highly purified enzyme, with a specific activity of 50, which corresponds to a 3,800 fold purification, and is almost homogeneous at the gel electrophoresis.

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