Some quantitative aspects of the passive sensitization of human basophils
Goldstein, B.; Dembo, M.; Malveaux, F.J.
Journal of Immunology 122(3): 830-833
1979
ISSN/ISBN: 0022-1767 PMID: 448077 Document Number: 144349
We review the theory for the binding of IgE to Fc receptors on basophil surfaces. We then use the theory to analyze binding experiments of Malveaux et al. and T. Ishizaka on the passive sensitization of basophils from a patient with chronic myelocytic leukemia and 75% basophilia. From their data we determine that the forward rate constant for the binding of human IgE to receptors on these human basophils is (3.0 +/- 1.0) x 10(4) M-1 sec-1.
Document emailed within 1 workday
Related Documents
Lett-Brown, M.A.; Mitchell, E.B.; Askenase, P.W. 1983: Sensitization of circulating basophils in guinea pig recipients of passive transfer of cutaneous basophil hypersensitivity (CBH) with immune serum: antigen-specific histamine release in vitro Journal of Immunology 130(5): 2104-2108Mitchell, R.W.; Rühlmann, E.; Magnussen, H.; Leff, A.R.; Rabe, K.F. 1994: Passive sensitization of human bronchi augments smooth muscle shortening velocity and capacity American Journal of Physiology 267(2 Pt 1): L218-L222
Dembo, M.; Goldstein, B.; Sobotka, A.K.; Lichtenstein, L.M. 1979: Degranulation of human basophils: quantitative analysis of histamine release and desensitization, due to a bivalent penicilloyl hapten Journal of Immunology 123(4): 1864-1872
MacGlashan, D.; White, J.M.; Huang, S.K.; Ono, S.J.; Schroeder, J.T.; Lichtenstein, L.M. 1994: Secretion of IL-4 from human basophils. The relationship between IL-4 mRNA and protein in resting and stimulated basophils Journal of Immunology 152(6): 3006-3016
Bandemir, B.; Ziegler, V.; Kipping, D.; Ebert, E.; Haustein, U.F. 1977: Atomic-absorption spectrophotometric determinations in quantitative problems of animal experimental sensitization. 2: Sensitization studies with potassium bichromate Dermatologische Monatschrift 163(5): 392-398
Martini, A.; Levy, M.; Broyer, M.; Hirsch, J.F.; Benveniste, J. 1978: Sensitization of basophils to a staphylococcus in glomerulonephritis secondary to an infection of a ventriculo-atrial bypass Journal d'Urologie et de Nephrologie 84(4-5): 349-353
Zhao, L.-M.; Xu, Y.-J.; Zhang, Z.-X.; Ni, W.; Chen, S.-X. 2004: Effect of passive sensitization by serum from allergic asthmatic patients on the activity and expression of voltage-dependent delayed rectifier potassium channel in human bronchial smooth muscle cells Chinese Medical Journal 117(11): 1630-1636
Massey, W.A.; Randall, T.C.; Kagey-Sobotka, A.; Warner, J.A.; MacDonald, S.M.; Gillis, S.; Allison, A.C.; Lichtenstein, L.M. 1989: Recombinant human IL-1 alpha and -1 beta potentiate IgE-mediated histamine release from human basophils Journal of Immunology 143(6): 1875-1880
Cinti, S.; Morroni, M.; Cangiotti, A.M. 1988: Quantitative morphologic aspects of the normal human parathyroid gland Bollettino della Societa Italiana di Biologia Sperimentale 64(5): 397-401
MacGlashan, D.; Guo, C.B. 1991: Oscillations in free cytosolic calcium during IgE-mediated stimulation distinguish human basophils from human mast cells Journal of Immunology 147(7): 2259-2269
Catalona, W.J.; Taylor, P.T.; Chretien, P.B. 1972: Quantitative dinitrochlorobenzene contact sensitization in a normal population Clinical and Experimental Immunology 12(3): 325-333
Kaben, U.; Westphal, H.J. 1976: Passive hemagglutination for the determination of humoral antibodies in fungus infections. II. Sensitization of erythrocytes and comparison of titers between hemagglutination and cell agglutination Dermatologische Monatschrift 162(5): 394-401
Chojnowski, W.; Gralewicz, J. 1976: Quantitative and qualitative aspects of the interaction of antibiotics with proteins. I. Binding of rifampicin and novobiocin to human blood albumin Acta Poloniae Pharmaceutica 33(2): 235-238
Hempstead, B.L.; Parker, C.W.; Kulczycki, A. 1979: Characterization of the IgE receptor isolated from human basophils Journal of Immunology 123(5): 2283-2291
Stavri, D.; Sorea, E.; Baroni, M. 1970: Quantitative determination of bacterial antigens with the passive hemagglutination technic Archives Roumaines de Pathologie Experimentales et de Microbiologie 29(4): 725-730
MacGlashan, D.W.; Schleimer, R.P.; Peters, S.P.; Schulman, E.S.; Adams, G.K.; Sobotka, A.K.; Newball, H.H.; Lichtenstein, L.M. 1983: Comparative studies of human basophils and mast cells Federation Proceedings 42(8): 2504-2509
MacGlashan, D.W.; Lichtenstein, L.M. 1981: The transition from specific to nonspecific desensitization in human basophils Journal of Immunology 127(6): 2410-2414
Schroeder, J.T.; MacGlashan, D.W.; MacDonald, S.M.; Kagey-Sobotka, A.; Lichtenstein, L.M. 1997: Regulation of IgE-dependent IL-4 generation by human basophils treated with glucocorticoids Journal of Immunology 158(11): 5448-5454
Warner, J.A.; Yancey, K.B.; MacGlashan, D.W. 1987: The effect of pertussis toxin on mediator release from human basophils Journal of Immunology 139(1): 161-165
Marone, G.; Findlay, S.R.; Lichtenstein, L.M. 1979: Adenosine receptor on human basophils: modulation of histamine release Journal of Immunology 123(4): 1473-1477