Methohexital clearance in patients with acute hepatitis
Richter, E.; Gallenkamp, H.; Heusler, H.; Zilly, W.; Breimer, D.D.
Medizinische Klinik 74(43): 1584-1588
1979
ISSN/ISBN: 0025-8458 PMID: 545102 Document Number: 143635
Pharmacokinetics of methohexital were studied in patients with acute hepatitis and after a treatment period either with "essential phospholipids" or phenobarbital. During the acute phase the distribution of methohexital was significantly altered. No change had been observed in the methohexital clearance. During remission the distribution of methohexital was in a normal range. After treatment with phenobarbital the methohexital clearance increased significantly whereas no change was observed after treatment with "essential phospholipids".
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