Plasmapheresis in the treatment of renal allograft rejections
Rifle, G.; Chalopin, J.M.; Turc, J.M.; Guigner, F.; Vialtel, P.; Dechelette, E.; Chenais, F.; Cordonnier, D.
Transplantation Proceedings 11(1): 20-26
1979
ISSN/ISBN: 0041-1345 PMID: 377632 Document Number: 142221
Thirty-four patients with renal allograft rejection unresponsive to conventional therapy underwent plasmapheresis. Twenty-four patients evidenced prompt and marked improvement and were discharged. Seventeen of these are presently stable off dialysis. Ten patients were not improved and required return to dialysis and/or transplant nephrectomy. Four hour warm, complement-dependent crossmatches which had become positive following transplant became negative following plasmapheresis in 3 patients who now have stable long-term function. Plasmapheresis appears promising in the treatment of refractory acute renal allograft rejection.