Polarographic determination of lipid hydroperoxides in the liver of guinea pigs on a varying allowance of ascorbic acid
Gazdarov, A.K.; Gazdarova, I.N.
Voprosy Meditsinskoi Khimii 25(5): 524-527
1979
ISSN/ISBN: 0042-8809 PMID: 494534 Document Number: 140634
As shown by polarographic method, administration of high doses of ascorbic acid into guinea pigs (100 mg per 100 g of body weight) within two weeks led to a distinct increase (2-fold) in concentration of endogenous peroxides in liver tissue. Maintaining of the animals on a diet, deficient in vitamin C, within 4 weeks (scorbutic animals) was accompanied by 1.6-fold decrease in content of lipid peroxides in liver tissue as compared with control group.