Hormonal balance in ovarian tumors
Smiller, R.R.; Shurygina, E.A.; Tiutiunova, A.M.; Il'inskaia, E.G.
Voprosy Onkologii 25(11): 68-72
1979
ISSN/ISBN: 0507-3758 PMID: 516570 Document Number: 140459
As a result of examining the urine excretion of 17-OCS, 17-KS, estrogens and the concentration of protein bound iodine and butanolextractable iodine in blood of patients with benign and malignant ovarian tumors, there were found some deviations from the normal hormonal balance in all these patients. These deviations were manifested in a delayed transformation of cortisol to cortisone, in a shifted androgeno-estrogenic balance toward estrogen active fractions, and in the reduced production of thyroid hormones. In ovarian cancer, however, these changes were manifested to a greater extent.