Pleiotropic phenotype of cultured murine cells resistant to maytansine, vincristine, colchicine, and adriamycin

Aldrich, C.D.

Journal of the National Cancer Institute 63(3): 751-757

1979


ISSN/ISBN: 0027-8874
PMID: 224236
Document Number: 140106
A noncloned subline of 3T3FL . Studies of binding and uptake of tritiated colchicine suggested that drug resistance of 3T3r cells might reflect decreased uptake of drug without decreased binding to surface receptors. Murine sarcoma virus transformed 3T3r cells less efficiently than 3T3FL cells.

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