Gonadotropin induced reproductive cyclicity in the domestic cat
Wildt, D.E.; Kinney, G.M.; Seager, S.W.
Laboratory Animal Science 28(3): 301-307
1978
ISSN/ISBN: 0023-6764 PMID: 682578 Document Number: 138730
Adult females were treated with FSH or PMS to induce ovarian follicle development and oestrus. Treatment involving single injections of FSH stimulated mature follicle development but resulted in inconsistent display of sexual receptivity and variable ovulation rates. Single or multiple injections of PMS induced follicle growth, but follicle rupture often occurred prior to oestrus and the mating stimulus. When compared to results obtained from females mated while in natural oestrus, cats receiving a series of injections of either gonadotropin demonstrated ovarian hypersensitivity and produced follicular cysts which failed to rupture. The most effective hormone regimen for inducing follicle growth and oestrus consisted of 2 mg FSH injected daily intramuscularly until oestrus. Females receiving this treatment were capable of ovulating following mating or HCG administration and were capable of conceiving if mated.