The antisteatosic activity of 2-MPG (Thiola) . Study with the (BSF) dynamic test and with liver biopsy before and after the treatment
Surrenti, C.; Arcangeli, A.; Casini, A.
Minerva Medica 69(61): 4251-4256
1978
ISSN/ISBN: 0026-4806 PMID: 733081 Document Number: 138066
The short-term therapeutic effect of 2-MPG has been studied in 12 patients suffering from chronic liver disease of prevalent steatosic type. The drug was administered in a dose of 2.5 g. for 20 days. Patients were submitted to hepatic needle biopsy and BSF load test, with compartmental analysis before and after treatment. A marked reduction in steatosis and a statistically significant fall in BSF retention at the 45th minute, with increase in conjugation and excretion of colorant, was observed in 11 patients.