The effect of maintenance dialysis on lymphocyte function. II. Peritoneal dialysis
Atkins, R.C.; Holdsworth, S.R.; Fitzgerald, M.G.; Hosking, C.S.
Clinical and Experimental Immunology 33(1): 102-106
1978
ISSN/ISBN: 0009-9104 PMID: 709906 Document Number: 138005
Lymphocyte function, as assessed by PHA-stimulated DNA synthesis, was studied in chronic renal failure patients maintained by peritoneal dialysis. In contrast to patients on haemodialysis, peritoneal dialysis patients had normal lymphocyte responsiveness pre-dialysis. There was no deterioration in the post-peritoneal dialysis plasma's ability to support control lymphocyte responsiveness as occurred after haemodialysis. Plasma dilution and reconstitution studies indicated that haemodialysis depleted the patients' plasma of nutrients and also added toxins, but peritoneal dialysis had neither effect.
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