Unusual evidence of myocardial involvement during a hypersensitivity reaction to oral penicillin

Herman, J.E.; Fleischmann, P.

Israel Journal of Medical Sciences 14(8): 848-851

1978


ISSN/ISBN: 0021-2180
PMID: 100472
Document Number: 137431
A hypersensitivity reaction to orally administered phenoxymethyl penicillin is reported. The manifestations of the reaction included fever, arthralgia, urticaria and an irregular pulse. Serial ECG showed second-degree atrioventricular block with junctional escape beats, an atypical Wenckebach pattern and, finally, first-degree atrioventricular block with gradually decreasing PR intervals. A normal tracing was recorded on the sixth day despite the persistence of the rash and joint pains.

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