Chemoneurolysis of the canine gastric submucosa. Effects on Heidenhain pouch secretion
Schapiro, H.; Jackson, N.J.; Rosato, F.E.; McDougal, H.D.; Chaudhuri, T.K.; Gayle, R.G.; Carwell, G.; Schapiro, M.B.
American Surgeon 44(12): 785-788
1978
ISSN/ISBN: 0003-1348 PMID: 736381 Document Number: 137144
Double denervated gastric pouches were constructed in dogs. One gastric pouch served as a control, and the other gastric pouch had its submucosa infiltrated with 25% ethyl alcohol (submucosal chemoneurolysis). Neurolysis of these gastric pouches did not alter their histological appearance but did eliminate their gastric secretory responses to histamine, meat and pentagastrin. The dogs exhibited elevated serum gastrin levels after feeding.