Failure to respond to influenza vaccine in the aged: correlation with B-cell number and function

Phair, J.; Kauffman, C.A.; Bjornson, A.; Adams, L.; Linnemann, C.

Journal of Laboratory and Clinical Medicine 92(5): 822-828

1978


ISSN/ISBN: 0022-2143
PMID: 309499
Document Number: 136818
Failure to respond to influenza vaccination correlated with a decreased number and percentage of IgD-bearing PBL and a dampened lymphocyte response to PWM in a subset of healthy aged volunteers. These subjects had normal levels of serum immunoglobulins, intact T cell function, and normal numbers of E-rosetting cells.

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