Granulomatous hepatitis: aetiological study of 107 cases
Vilaseca, J.; Guardia, J.; Cuxart, A.; Clotet, V.; Martinez-Vasquec, J.M.; Bernado, L.; Masana, L.; Garcia-Vanrell, G.; Bacardi, R.
La Nouvelle Presse Medicale 7(37): 3323-3325
1978
ISSN/ISBN: 0301-1518 PMID: 733501 Document Number: 135632
In this series, the commonest aetiology was tuberculosis (30 cases, 28%), followed by sarcoidosis (18 cases, 17,7%), mediterranean fever (Olmer's disease) (13 cases, 12,1%), brucellosis (8 cases, 7,4%), typhoid fever (7 cases, 6,6%) and idiopathic forms (8 cases, 7,4%). These were followed by Hodgkin's disease, toxoplasmosis, adenosarcoma, and leprosy. Finally, there were single cases due to infectious mononucleosis, B.C.G. reaction, hypogammaglobulinaemia, coeliac disease and temporal arteritis. Half of the patients had hepatomegaly and an increase, in general moderate, in hepatic enzymes (transaminases, alkaline phosphatase). The highest enzyme levels were seen in cases of brucellosis, hepatic enzymes being normal in patients with sarcoidosis.