Role of the pituitary-adrenal system in mechanism regulating vascular permeability during stress
Gorizontova, M.P.; Chernukh, A.M.; Deshevoĭ, I.B.
Biulleten' Eksperimental'noi Biologii i Meditsiny 85(2): 139-142
1978
ISSN/ISBN: 0365-9615 PMID: 630081 Document Number: 135543
Disturbances of the microvascular permeability were studied by the "vascular labelling" technique during the immobilization stress of hypophysectomized and adrenalectomized rats. Animals with sham operations served as controls. As revealed, hypophysectomy and adrenalectomy caused disturbances of vascular permeability in the mesentery. Vascular permeability disturbances in the hypophysectomized and adrenalectomized rats under conditions of immobilization were more expressed than in the sham-operated animals. Removal of the pituitary and adrenal glands produced mast cell degranulation at the earlier immobilization period.