Metabolic dysfunction and chronic stress: a new sight at "diabesity" pandemic
Gastaldi, G.; Ruiz, J.
Revue Medicale Suisse 5(206): 1273-1277
2009
ISSN/ISBN: 1660-9379 PMID: 19579423 Document Number: 13537
Chronic stress in Western society can activate the autonomus, neuroendocrine and inflammatory/immunlogic systems. Chronic exposure to stressors can indeed stimulate the hypothalamic-pituitary-adrenal axis and induce a disbalance between anabolic and catabolic hormones, responsible of an increased in visceral fat and of insulin resistance. These metabolic consequences can lead to pre-diabetes. Exposure to chronic stress results in allostatic load and its pathophysiologic consequences. The knowledge of this mecanisms and the cardiovascular and metabolic risk related, should influence our way of thinking about patient care. To decrease allostatic load, practitioners can rely on therapeutic relation. Therapeutic education is one of the skill that can be use to create therapeutic relation.
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