The anomalies of limbs obtained by injections of cyclophosphamid to the pregnant rabbit

Clavert, J.M.; Brun, B.; Clavert, A.; Buck, P.

Chirurgie Pediatrique 19(3): 205-207

1978


ISSN/ISBN: 0180-5738
PMID: 709722
Document Number: 135189
By injections of cyclophosphamid to pregnant rabbits, we obtained different sorts of agenesis. These anomalies are the consequence of a lack of the quantity of mesenchyme necessary to the formation of the limbs. The final malformation depends on the date, the dose and the period of action of the cyclophosphamid.

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