Critical period in the work of the form-inducing apparatus of the lens in chick embryos, detected after chloramphenicol application
Puchkov, V.F.
Arkhiv Anatomii Gistologii i Embriologii 74(2): 50-54
1978
ISSN/ISBN: 0004-1947 PMID: 646636 Document Number: 134161
The inhibitor of protein synthesis chloramphenicol (2 mg/egg) was applied to elucidate the critical period in the chicken lens development. Chloramphenicol injected before incubation and at 24, 30 and 48 h of incubation did not prevent the formation of parts in the lens-inducing apparatus (the optic vesicle, and the presumptive lens ectoderm), but the injection at the stage of 24--30 h of incubation resulted, in many survived for 5--7 days of incubation, in lack of the lens. Therefore, it is possible to speak about a disturbance in the activity of the inducing apparatus during the period of determination, or about a critical period of the lens development.