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Quantitative cytochemical study of local immunostimulation of the respiratory mucosae by mineral spa water

Chevance, L.G.; Lesourd, M.

La Nouvelle Presse Medicale 7(30): 2625-2627

1978

ISSN/ISBN: 0301-1518
PMID: 693298
Document Number: 132996
After non-specific stimulation (by mineral spa water) of the secretion of IgA by the respiratory tract of rabbits, the animals were killed and a study made of the number of plasmocytes per 500 diameter field by phase contrast microscopy. The number of plasmocytes was markedly increased on the 15th day and remained 5 times higher than in control animals on the 100th day. Immunocytochemical labelling by the secretory anti-IgA Fab fraction confirmed these data electron microscopically.

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