Systemic lupus erythematosus with negative LE cells and antinuclear factor
Gladman, D.D.; Chalmers, A.; Urowitz, M.B.
Journal of Rheumatology 5(2): 142-147
1978
ISSN/ISBN: 0315-162X PMID: 78982 Document Number: 132715
In the course of a prospective study of 165 patients with SLE a subgroup of eight patients with active SLE yet with persistently negative tests for ANF and LE cells was identified. These patients were characterized by a photosensitive skin rash with a negative lupus band test, a high incidence of arthritis, mild form of renal disease, and a positive family history for connective tissue disease. Antibodies to DNA and cytoplasmic antigens were detected in a few.
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