Doxycycline (Vibramycin) in pelvic inflammatory disease
Gjønnaess, H.; Holten, E.
Acta Obstetricia et Gynecologica Scandinavica 57(2): 137-139
1978
ISSN/ISBN: 0001-6349 PMID: 345730 Document Number: 132407
Using standardized laparoscopy technique, fluid was aspirated from the pouch of Douglas, from the Fallopain tubes and from ovarian cysts in 85 . The concentration of doxycycline in the aspirates was measured after oral ingestion of 200 mg of doxycycline (Vibramycin). A therapeutic level was achieved in the tubes and in ovarian cysts within a few hours, and on continuation of the treatment these values followed the plasma concentration closely, still being within the therapeutic range 24 h after the final dose. The clinical effect was excellent, 94% (60/64) of the cases with verified PID being cured by doxycycline.