Studies on the control of pineal indole synthesis: cyclic nucleotides, adenylate cyclase and phosphodiesterase
Oleshansky, M.A.; Neff, N.H.
Journal of Neural Transmission. Supplementum 13: 81-95
1978
ISSN/ISBN: 0303-6995 PMID: 38299 Document Number: 132353
An overview of the biochemical events that occur when postsynaptic pineal beta-adrenergic receptors are stimulated is presented. Emphasis is placed on the importance of the adenylate cyclase system for the induction of N-acetyltransferase (NAT). Super- and subsensitive responses of NAT to receptor agonists are related to cAMP concentration, adenylate cyclase and phosphodiesterase activities and receptor binding sites.
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