Enhancement phenomenon in mice with a heterotopic heart transplant
Frolova, M.A.; Gudkova, R.G.; Bol'shukhina, L.A.; Novoselova, V.N.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 10: 36-40
1978
ISSN/ISBN: 0372-9311 PMID: 85397 Document Number: 131692
A possibility of enhancement induction with the aid of a preparation of lymphocyte membranes of the spleen of donor specificity in its combination with antimouse horse globulin was studied on mice with heterotopic graft of the heart. As shown, in recipients with prolongation of the graft electrical activity lymphocytes retained their reaction to donor antigens, whereas the blood serum produced an enhancement effect in its administration to syngeneic recipients.