Tuberculosis: review of treatment failure, relapse and drug resistance
Guernsey, B.G.; Alexander, M.R.
American Journal of Hospital Pharmacy 35(6): 690-698
1978
ISSN/ISBN: 0002-9289 PMID: 352145 Document Number: 131592
Factors affecting the success and failure of tuberculosis (TB) treatment programs are reviewed. Topics covered include incidences of primary and secondary resistance; methods and probability of bacteriologic transfer of resistance; factors affecting delivery of successful treatment of TB; and retreatment concepts, history and regimens for TB relapse and treatment failures. Isoniazid, rifampin and ethambutol hydrochloride produce a high percentage of cure in initial and retreatment TB therapy. Attention to patient compliance should be emphasized to assure effective treatment.
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