Study report on the lack of interaction between mianserine and noradrenaline in man
Ghose, K.
Fortschritte der Medizin 96(25): 1343-1344
1978
ISSN/ISBN: 0015-8178 PMID: 669524 Document Number: 131313
Tricyclic antidepressants are known to potentiate the increase in blood pressure caused by noradrenaline. Five depressive patients were given intravenous noradrenaline before and after 2--4 weeks of treatment with Org GB 94 (Tolvin). The dose of noradrenaline was increased until a rise of 30 mmHg in systolic blood pressure occurred. No evidence of interaction between Org GB94 and noradrenaline was found. The implications of this are discussed.
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