Symmetric cerebral calcification associated with disturbed parathyroid function
Keck, E.; Schuier, F.J.; Thörner, G.; Ischebeck, W.; Durdel, R.; Wiegelmann, W.
Medizinische Klinik 73(43): 1507-1512
1978
ISSN/ISBN: 0025-8458 PMID: 713955 Document Number: 131292
Alteration of the metabolism of calcium and phosphate may be associated with symmetric cerebral calcification. Detailed investigations of the function of parathyroid glands including computer tomography of the brain are so far missing. In 6 patients with clinical and biochemical signs of altered function of the parathyroid glands symmetric cerebral calcification could be demonstrated by computer tomography. They are also visible by X-ray examination in one patient. Consequently, functional disturbances of the brain, cerebellum and of the extrapyramidal system may occur. Moreover, the combination of hypoparathyroidism and hypothyroidism also appears to result in the development of symmetric cerebral calcification. The pathogenesis of the calcification as well as therapeutic approaches will be discussed.