N-Demethylation of cocaine in the rat and in isolated rat hepatocytes: comparison with aminopyrine demethylation
Stewart, D.J.; Inaba, T.; Kalow, W.
Journal of Pharmacology and Experimental Therapeutics 207(1): 171-177
1978
ISSN/ISBN: 0022-3565 PMID: 702338 Document Number: 131225
Document emailed within 1 workday
Related Documents
Erickson, R.R.; Yu-Drent, P.; Holtzman, J.L. 1982: The kinetics of ethylmorphine N-demethylation in isolated hepatocytes: the effect of drug transport and oxygen concentration Journal of Pharmacology and Experimental Therapeutics 220(1): 35-38Jansson, I.; Schenkman, J.B. 1981: Stoichiometry of aminopyrine demethylation with and without NADH synergism Drug Metabolism and Disposition: the Biological Fate of Chemicals 9(5): 461-465
Bátkai, L.; Nográdi, M.; Farkas, L.; Feuer, L.; Horváth, I. 1973: Demethylation of 7-methoxyisoflavone by Penicillium cyclopium Archiv für Mikrobiologie 90(2): 165-166
Hu, J.; Kulkarni, A.P. 2002: Lipoxygenase-mediated N-demethylation of pesticides in vitro Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 20(6): 409-412
Flynn, E.J.; Spector, S. 1974: Radioimmunoassay for hepatic N-demethylation of metharbital in vitro Journal of Pharmacology and Experimental Therapeutics 189(2): 550-556
Dunn, J.D.; Clarkson, T.W. 1980: Does mercury exhalation signal demethylation of methylmercury? Health Physics 38(3): 411-414
Dawson, G.W.; Vestal, R.E. 1984: Cimetidine inhibits the in vitro N-demethylation of methadone Research Communications in Chemical Pathology and Pharmacology 46(2): 301-304
Campbell, R.L.; Suppnick, J.D.; Hettrick, J.M.; Nigro, N.D. 1978: Rat liver microsome-mediated N-demethylation and mutagenicity of azoxymethane Cancer Research 38(12): 4585-4590
Hollenberg, P.F.; Miwa, G.T.; Walsh, J.S.; Dwyer, L.A.; Rickert, D.E.; Kedderis, G.L. 1985: Mechanisms of N-demethylation reactions catalyzed by cytochrome P-450 and peroxidases Drug Metabolism and Disposition: the Biological Fate of Chemicals 13(3): 272-275
Moisand, C.; Moisand, A.; Pitet, G. 1972: Oxidative demethylation of tetramethylurea by rat (Wistar A.G.) liver microsomes Annales Pharmaceutiques Francaises 30(11): 767-773
Guz, J.; Foksiński, M.; Oliński, R. 2010: Mechanism of DNA methylation and demethylation--its role in control of genes expression Postepy Biochemii 56(1): 7-15
Zhang, H.; Xiao, W.; Liang, H.; Fang, D.; Yang, S.; Luo, Y. 2002: Demethylation in the promoter area by the antisense of human DNA MTase gene Zhonghua Zhong Liu Za Zhi 24(5): 444-447
Thompson, J.A.; Holtzman, J.L. 1977: Studies on the N-demethylation and O-de-ethylation of ethylmorphine by hepatic microsomes from male rats Drug Metabolism and Disposition: the Biological Fate of Chemicals 5(1): 9-14
Kersh, E.N.; Fitzpatrick, D.R.; Murali-Krishna, K.; Shires, J.; Speck, S.H.; Boss, J.M.; Ahmed, R. 2006: Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells Journal of Immunology 176(7): 4083-4093
Estévez, F.; Giusti, M.; Parrillo, S.; Oxandabarat, J. 1996: Enzyme polymorphism on the metabolic O-demethylation of dextromethorphan in a South American population Medicina 56(4): 378-382
Lui, E.M.; Gregson, J.; Lucier, G.W. 1981: Altered sex differentiation of hepatic ethylmorphine N-demethylation in the male rat following neonatal methadone exposure Pediatric Pharmacology 1(3): 187-195
Ginder, G.D.; Whitters, M.; Kelley, K.; Chase, R.A. 1983: In vivo demethylation of chicken embryonic beta-type globin genes with 5-azacytidine Progress in Clinical and Biological Research 134: 501-510
Moody, D.E.; Alburges, M.E.; Parker, R.J.; Collins, J.M.; Strong, J.M. 1997: The involvement of cytochrome P450 3A4 in the N-demethylation of L-alpha-acetylmethadol (LAAM), norLAAM, and methadone Drug Metabolism and Disposition: the Biological Fate of Chemicals 25(12): 1347-1353
Rogalski, J.; Hatakka, A.; Leonowicz, A. 2000: Demethylation of [14C]-labelled veratric acid and oxidation of methanol and formaldehyde by the white-rot fungus Phlebia radiata Acta Microbiologica Polonica 49(3-4): 207-216
Fang, X.-m.; Sun, L.-f.; Peng, J.-p.; Dong, Q.; Zheng, S. 2003: The study of 5-Aza-2'-deoxycytidine on transcription regulation of p16/CDKN2 gene demethylation in RKO human colorectal cell line Zhonghua Yi Xue Za Zhi 83(23): 2077-2082