Antibody-forming cells in rat spleen following midbrain injury
Gol'dshteĭn, M.M.
Biulleten' Eksperimental'noi Biologii i Meditsiny 85(2): 185-187
1978
ISSN/ISBN: 0365-9615 PMID: 630094 Document Number: 130472
The number of plaque-forming cells (PFC) in the spleen of rats immunized with sheep red blood cells after the injury of the anterior or the posterior portions of the medial hypothalamus, and also of the thalamus displayed no significant difference from the number of PFC in the spleen of intact animals. The titres of hemolysing and hemagglutinating antibodies in the animals with injuries of the mid-brain were somewhat lower than in the intact animals. A reduction of the circularing antibodies level was not associated with localization of the foci of injury and apparently served as the sequence of the craniocerebral trauma.