Arhinencephaly detected by a pitressin-sensitive diabetes insipidus
Palcoux, J.B.; Guesry, P.; Czernichow, P.; Broyer, M.
Archives Francaises de Pediatrie 35(9): 998-1003
1978
ISSN/ISBN: 0003-9764 PMID: 747508 Document Number: 129180
A 4-month old child presented with facial malformations and severe hypernatremia. Hypernatremia was secondary to diabetes insipidus due to a disorder of ADH secretion, associated with cerebral malformations. Clofibrate treatment was ineffective. However, after the patient was treated by a low osmotic residue diet, an increased water-intake and hydrochlorothiazide, natremia became normal and growth resumed.