Models of inhibition in animal behavior
Soubrie, P.; Chermat, R.; Poncelet, M.; Simon, P.
L'Encephale 4(5 Suppl): 503-511
1978
ISSN/ISBN: 0013-7006 PMID: 38103 Document Number: 128866
The concept of inhibition in psychopharmacology is discussed by presenting different models of behavioral inhibition in animals. The inhibitions induced by fear or anxiety appear as a result of punishment introduction into an unknown situation, frustration... These inhibitions are particularly sensitive to minor tranquilizers. The inhibitions induced by "fatigue" appear when avoidance situations continue for 24 hours or when a situation demands a marked increase of animal activity to obtain the same reward (food). These inhibitions are particularly sensitive to psychoanaleptics. The inhibition induced by placing a animal in an inescapable situation is particularly sensitive to antidepressants.