Hyaluronidase in meningococcus

Mironova, T.K.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 2: 91-93

1978


ISSN/ISBN: 0372-9311
PMID: 96634
Document Number: 128045
A total of 204 meningococcus strains were tested for the presence of hyaluronidase, and 45.5% of the strains were found to contain it. Strains penetrating into the cerebrospinal fluid were the ones which largely produced the enzyme (in 83% of the cases). The enzyme was revealed only in 25.5% of the strains habituating on the nasopharyngeal mucosa. Hyaluronidase was mostly found in the meningococcus strains referred to the serological group A; strains of other serological groups and ungrouped strains produced the enzyme in 23.7% of the case only. There was no correlation between the capacity to form hyaluronidase and the virulence determinable in intraperitoneal infection of mice.

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