Top Abstract Purchase Related
Home
>
Node
>
Subnode

Study of the effect of rimantadine on the course of mixed viral-bacterial infection in albino mice

Zastavnyĭ, I.V.; Shablovskaia, E.A.; Loziuk, L.V.; Volos, O.P.; Shloma, B.V.

Voprosy Virusologii 1: 79-81

1978

ISSN/ISBN: 0507-4088
PMID: 347720
Document Number: 127830
The results of the study of rimantadine effectiveness in a viral-bacterial infection in white mice caused by a mixture of influenza A2 virus (10 LD50) and hemolytic streptococcus group A (350 million bacteria). The drug showed no prophylactic or therapeutic effect in the mixed infection, whereas in influenza infection in the animals which served as a positive control rimantadine had marked antiviral activity (P less than 0.001). It is assumed that the lack of the drug effectiveness against the mixed infection is due to the formation in the animals of virus-microbe complexes which are conducive to an increase of infectious virus titers and virus resistance to various treatments.

Document emailed within 1 workday
Secure & encrypted payments

Degré, M.; Solberg, L.A. 1971: Synergistic effect in viral-bacterial infection. 3. Histopathological changes in the trachea of mice following viral and bacterial infection Acta Pathologica et Microbiologica Scandinavica. Section B: Microbiology and Immunology 79(2): 129-136
Rakovskaia, I.V. 1985: Persistence of M. arthritidis and the Rauscher leukemia virus in a mixed Mycoplasma-viral infection in mice Vestnik Akademii Meditsinskikh Nauk SSSR 3: 32-38
Kowalska, M.; Denys, A.; Szydłowska, T.; Białek, J. 1985: The influence of isoprinosine (ISO) on some cell immunity parameters in mice infected with influenza viruses and in mixed viral-bacterial infections. II. Phagocytosis and bactericidal activity of granulocytes Archivum Immunologiae et Therapiae Experimentalis 33(6): 741-753
Essel', A.E.; Seleznev, V.A. 1975: Effect of a mixed E. coli O-111 (RNA-azopositive and RNA-azonegative strains) and Coxsackie B3 viral infection on oxygen demand and on the succinate dehydrogenase activity of an HEp-2 cell culture according to polarographic study data Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 10: 50-55
Bikbulatov, R.I.; Gerasimova, A.V.; Moĭsiadi, S.A.; Stakhanova, V.M. 1974: Experimental study of a mixed influenza and herpes viral infection Voprosy Virusologii 5: 532-535
Krichevskaia, G.I.; Murav'eva, T.V.; Vonogradova, V.L.; Slepova, O.S. 1976: Method of study of conjunctival scrapings for diagnosis of mixed viral infection of the anterior portion of the eye Laboratornoe Delo 9: 571-572
Kagan, G.I.; Postnikova, Z.A.; Rakovskaia, I.V.; Margunova, T.D.; Bykovskiĭ, A.F. 1976: Role of mixed mycoplasma-viral infection in viral leukemogenesis Vestnik Akademii Meditsinskikh Nauk SSSR 5: 86-93
Dmitriev, G.A. 1990: Mixed bacterial and viral infections of the urogenital tract Vestnik Dermatologii i Venerologii 6: 29-33
Ivanovskaia, T.E.; Kask, L.N.; Pokrovskaia, L.I. 1992: The problem of septicemia, bacterial shock and generalized viral-bacterial infection in childhood Arkhiv Patologii 54(11): 39-41
Moisa, I.; Demetrescu, R. 1970: Comparative studies of the susceptibility of some lines of mice to influenza viruses. I. Experimental study of some strains of type a and A2 in A2G, CBA, C3H (hybrid) and albino mice Studii Si Cercetari de Inframicrobiologie 21(2): 111-117
Ryzhkova, V.V.; Pavlovich, N.V.; Makarovskaia, L.N.; Zurabian, V.A.; Bespalova, I.A.; Goncharov, E.K.; Bugaeva, O.K.; Malsova, N.N. 1996: Increased effectiveness of etiotropic therapy of experimental plague in albino mice at the stage of generalized infection Antibiotiki i Khimioterapiia 41(2): 35-39
Maksimov, V.A.; Baliabin, A.A.; Dygin, V.P.; Pervomaĭskiĭ, A.G.; Topleninova, K.A. 1971: Myocardial involvement in experimental influenza and mixed (viral-staphylococcal) infection Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 15(1): 21-25
Amara, R.O.; Aburawi, S.M. 2008: Pyridoxine effect on the antidepressant action of imipramine in albino mice Saudi Medical Journal 29(11): 1554-1557
Stefanowicz, M.; Szozda, J.; Dyner, E. 1988: Effect of Streptococci on epithelial cells of the vagina of albino inbred mice NMRi Patologia Polska 39(3): 210-219
Valzelli, L.; Kozak, W.; Giraud, O. 1987: Difference in learning and retention by Albino-Swiss mice. Part IV. Effect of some nutrients Methods and Findings in Experimental and Clinical Pharmacology 9(1): 5-8
Hall, C.B.; Dolin, R.; Gala, C.L.; Markovitz, D.M.; Zhang, Y.Q.; Madore, P.H.; Disney, F.A.; Talpey, W.B.; Green, J.L.; Francis, A.B. 1987: Children with influenza a infection: treatment with rimantadine Pediatrics 80(2): 275-282
Cavusoglu, K.; Oruc, E.; Yapar, K.; Yalcin, E. 2009: Protective effect of lycopene against mercury-induced cytotoxicity in albino mice: pathological evaluation Journal of Environmental Biology 30(5 Suppl): 807-814
Woźniak, D.; Pezioł-Laszczyńska, M.; Ołowska, L. 1981: Effect of long-term phenol administration on morphological and histoenzymatic changes in the kidneys of albino mice Roczniki Panstwowego Zakladu Higieny 32(1): 61-67
Munoz-Fontela, C.; Garcia, M.Angel.; Garcia-Cao, I.; Collado, M.; Arroyo, J.; Esteban, M.; Serrano, M.; Rivas, C. 2005: Resistance to viral infection of super p53 mice Oncogene 24(18): 3059-3062
Bekhalo, V.A.; Sysoliatina, E.V.; Nagurskaia, E.V. 2009: Mechanisms of Chlamydia trachomatis and herpes simplex virus persistence during viral-bacterial infection Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 55(5): 105-110