Thymidine phosphorylation with the participation of rat thymic and hepatic thymidine kinase in the presence of a factor from Cl. perfringens (welchii)
Siluianova, S.N.; Eremenko, V.V.
Voprosy Meditsinskoi Khimii 24(2): 184-188
1978
ISSN/ISBN: 0042-8809 PMID: 208287 Document Number: 127289
Factor CPW, isolated from Cl. perfringens/welchii was shown to activate latent thymidine kinase (factor N) from liver tissue of rats beginning from 42 days age. CPW factor activated 3.5-fold also thymidine kinase from rat strumous gland; the enzyme was observed during involution of the tissue. The data suggest that increase in thymidine kinase activity in proliferating tissues is related to activation of latent enzymes.