The use of tobramycin in severe infections
Babinet, P.; Bricaire, F.; Tancrede, C.; Goulon, M.
La Semaine des Hopitaux Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 54(33-36): 1049-1054
1978
ISSN/ISBN: 0037-1777 PMID: 220716 Document Number: 126414
The interest of tobramycin, studied here in 63 cases of severe infection, is due to several factors: --its ease of use including in cases of renal insufficiency; --the efficiency of subcutaneous administration, of particular interest to patients on anticoagulants; --its action on multi-resistant Enterobacteria and those not responding to gentamicin. Antibiotherapy is however only one of the elements of success in the treatment of severe infections, beside two factors which are often linked and determining: early treatment and the development of foci resistant to antibiotics.