Hoigne reaction and its modifications
Klemparskaia, N.N.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 7: 31-37
1978
ISSN/ISBN: 0372-9311 PMID: 358701 Document Number: 126233
The author analyzes 114 works published lately dealing with methodical improvement of Hoigne's reaction and its application both in experimental studies and in clinical practice. The great majority of the works (over 90) were referred to the use of modification of this reaction suggested by Klemparskaya and Raeva for detection of autoantibodies to the lysate of autoerythrocytes and organ extracts. This reaction was found to be useful for studying the autosensitization process in man and animals; its prognostic significance at the clinic was of importance since its intensity corresponded to the severity of the process and promptly decreased with effective treatment.