Phase Ii study of triazinate and pyrazofurin in patients with advanced breast cancer previously exposed to cytotoxic chemotherapy
Nichols, W.C.; Kvols, L.K.; Ingle, J.N.; Edmonson, J.H.; Ahmann, D.L.; Rubin, J.; O'Connell, M.J.
Cancer Treatment Reports 62(5): 837-839
1978
ISSN/ISBN: 0361-5960 PMID: 657166 Document Number: 125684
The purpose of this phase II clinical trial was to evaluate the effectiveness of triazinate and pyrazofurin in the treatment of advanced breast cancer. Although an occasional patient experienced stability of disease, neither agent, as employed in this study, was able to produce an objective antitumor effect in this group of patients with previous chemotherapeutic exposure. At the dosages used in this study, neither agent can be recommended for further treatment of advanced breast cancer.
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