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Psychoactive drug interactions

Gaultieri, C.T.; Powell, S.F.

Journal of Clinical Psychiatry 39(9): 720-729

1978

ISSN/ISBN: 0160-6689
PMID: 29033
Document Number: 125661
Interactions can arise from serial or simultaneous administration of 2 or more drugs. Interactions with other medications can enhance or diminish either the clinical usefulness of a drug, or its toxic effects. Interactions can arise from changes in absorption, protein binding, metabolism, excretion or activity at a common site of action. Drug interactions of clinical interest to psychiatrists are described. The drugs include: stimulants, neuroleptics, tricyclic antidepressants, monoamine oxidase inhibitors, lithium, anticonvulsants, and sedatives and hypnotics.

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