Cartilage metabolism experimentally influenced by osteotropic hormones

Havelka, S.; Babický, A.; Musilová, J.; Tesárek, B.; Rohozková, D.

Casopis Lekaru Ceskych 117(20): 617-619

1978


ISSN/ISBN: 0008-7335
PMID: 208772
Document Number: 124648
The effect was studied of parathyrin, calcitonin and cholecalciferol on articular, xiphoid and auricular cartilage in rabbits by means of 35S incorporation in vivo. The effect of parathyrin showed as a significant increase in 35S incorporation in the articular cartilage unlike calcitonin and vitamin D where there was no such effect. However, cholecalciferol apparently had a stabilizing effect on articular cartilage collagen. The other two types of cartilage remained unaffected by the osteotropic agents used; incorporation of 35S was each time much less than in articular cartilage.

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