Action of O-beta-diethylaminoethylhydroxylamine on bacteriophage T2
Khromov, I.S.; Ulanov, B.P.; Tikhinenko, T.I.
Voprosy Virusologii 4: 497-501
1977
ISSN/ISBN: 0507-4088 PMID: 919505 Document Number: 124203
A chemical modification of T2 phage DNA by O-beta-diethylaminoethylhydroxylamine was studied in situ. In the course of the reaction, cross-links between DNA and protein of the phage particle develop. The DNA-protein interaction contributes to the nucleophilic joining of hydroxylamine derivatives by C5-C6 double bond of 5-oxymethylycytosine which is a constituent of T2 phage DNA.
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