Intracytoplasmic type A particles in viper spleen cells
Lunger, P.D.; Clark, H.F.
Journal of the National Cancer Institute 58(3): 809-811
1977
ISSN/ISBN: 0027-8874 PMID: 190419 Document Number: 121593
Structures resembling typical type A particles were observed in paranuclear inclusions in cultured C-type particle-producing viper cells (VSW cell line). The incidence of type A particle inclusions was low (approximately 0.5% of cell profiles examined) in untreated cells, but both the incidence and size of the inclusions were slightly increased in cells treated with ethidium bromide. This is apparently the first observation of type A particles in cells of a poikilothermic vertebrate.
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