Cyclic nucleotides and prostaglandins (PGs) produced by the rabbit oviduct: effects of estrogen treatment

Valenzuela, G.; Antonini, R.; Hodgson, B.J.; Jones, D.J.; Harper, M.J.

Research Communications in Chemical Pathology and Pharmacology 17(2): 361-364

1977


ISSN/ISBN: 0034-5164
PMID: 195319
Document Number: 121579
Levels of cyclic AMP and cyclic GMP have been measured in oviducts of rabbits killed 68 hr after injection of human chorionic gonadotrophin (HCG) to induce ovulation. cAMP and cGMP levels were higher in the isthmus than in the ampulla. Estrogen treatment given at the same time as HCG increased cGMP levels. Levels of PGE and PGF in blood draining the oviduct were low and showed no effect of estrogen treatment at 68 hr after HCG.

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