Hyperparathyroidism in deficiency rickets. Changes after vitamin therapy
Mallet, E.; Bousnina, S.; Tron, P.; Basuyau, J.P.; Brunelle, P.; de Menibus, C.H.
Archives Francaises de Pediatrie 34(7): 632-638
1977
ISSN/ISBN: 0003-9764 PMID: 201225 Document Number: 121309
The study concerned 16 cases of deficiency rickets observed over 3 years. The level of serum parathyroid (IPTH) hormone was always increased in the late stages of rickets, but was normal in 3 cases of early rickets with hypocalcaemia and monophosphataemia. There was no statistical correlation between the level of IPTH and monophosphataemia. There was no statistical correlation between the level of IPTH and calcaemia. After vitamin D-therapy, the levels if IPTH returned to normal in 5 to 21 days in most cases. No obvious difference was noted in this evolution between children treated by vitamin D2 and 25 OH D. The excretion of urinary cyclic adenosine monophosphate decreases in parallel with blood IPTH.