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A critical analysis of platelet counting methods

Wertz, R.K.; Koepke, J.A.

American Journal of Clinical Pathology 68(1 Suppl): 195-201

1977

ISSN/ISBN: 0002-9173
PMID: 879094
Document Number: 119923
A careful analysis of platelet counting methods, including an assessment of accuracy, was done using data from the College of American Pathologists Comprehensive Hematology Survey preserved platelet suspension specimen (H-32-1976). Comparisons between methods suggest systematic biases probably related to the calibration methods used for automated instruments. Falsely elevated counts occurred with manual methods and one light-dispersion system. Methods for calibration and continuing quality assurance of platelet counting are proposed.

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