Hexokinase activity in blood serum during carcinogenesis
Kil'dema, L.A.
Voprosy Onkologii 23(1): 45-48
1977
ISSN/ISBN: 0507-3758 PMID: 193294 Document Number: 119631
During carcinogenesis, induced by diethylnitrosamine in rats Wistar (in doses of 2.5 mg per Kg of weight daily with drinking water), the hexokinase (HK) activity in blood serum was observed with the appearance of the first morphological symptoms of tumor growth. It is observed mainly starting from the first months. At the end of the experimental period (8-9th month), when hepatomas develop in the liver, the HK activity in blood serum was noted almost in all cases. No serum HK activity was found in control rats.