Decrease of insulin growth factor-1 as a novel mechanism for anti-androgen effect of isotretinoin and its reported association with depression in some cases
Feily, A.; Namazi, M.R.
Journal of drugs in dermatology JDD 10(7): 793-794
2011
ISSN/ISBN: 1545-9616 PMID: 21720662 Document Number: 11919
Isotretinoin and its desirable effects have received tremendous attention in recent years by scientists. This article reviews the evidence that decrease of insulin growth factor-1 is implicated as a novel mechanism of anti androgenic effect and its reported association with depression in some cases.
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