Deficienty of specific HLA antibodies in severe pregnancy pre-eclampsia/eclampsia
Jenkins, D.M.; Need, J.; Kajah, S.M.
Clinical and Experimental Immunology 27(3): 485-486
1977
ISSN/ISBN: 0009-9104 PMID: 862235 Document Number: 119173
The paradox of the survival of the fetal allograft remains unresolved as does the etiology of pre-eclampsia/eclampsia.sbd.the principle disease of pregnancy. In a prospective study of very severe cases of pre-eclampsia, significantly reduced antibody to paternal histocompatibility antigens was found. A lowered immune response to the fetal allograft may play a role in severe cases of pre-eclampsia.
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